Synthesis and characterization of Ru(II) complexes with polyfunctional quinazo line-(3H)-4-ones

1066-1069A few Ru(II) complexes of the type Ru (O – N - O)2 with tridentate O – N - O donors and of the type RuCl2(O-N)2 with bidentate O - O and O – N donors have been synthesized and characterized on the basis of analytical, conductivity, thermal, magnetic, IR, electronic and PMR spectral data. The IR and PMR spectral data of the metalcomplexes indicate that the ligands like 2-methyl/phenyl-3- (2'-hydroxybenzalamino) quinazoline-(3H)-4-one (MHBQ/ PHBQ) act as uninegative tridentate, 2-methyl/phenyl- 3-(carboxymethyl) quinazoline-(3H)-4-one (MCMQ/PCMQ) as uninegative bidentate and 2-methyl/phenyl-3-(furfuralamino) quinazoline-(3H)-4-one (MFQ/PFQ), 2-methyl/phenyl-3-(acetamino) quinazoline-(3H)-4-one (MAQ/PAQ), 2-methyl/phenyl 3-(uramino) quinazoline- (3H)-4-one (MUQ/PUQ) and 2-methyl/phenyl-3- thiouramino)quinazoline-(3H)-4-one-(MTUQ/PTUQ) as neutral bidentate ligands.The electronic spectral data of the complexes indicate that the arrangement around Ru(II) is octahedral

Effect of Organo Montmorillonite Nanoclay on Mechanical Properties Thermal Stability and Ablative Rate of Carbon fiber Polybenzoxazine Resin Composites

Organo-Montmorillonite (o-MMT) nanoclay added polybenzoxazine resin (type I composites) were prepared with varying amounts of clay (0, 1, 2, 4 and 6 wt %). Clay dispersion, changes in curing behaviour and thermal stability were assessed in type I composites. Findings from these studies of type I composites were used to understand thermal stability, mechanical, and mass ablation rate behaviour of nanoclay added carbon fiber reinforced polybenzoxazine composites (type II). Interlaminar shear strength and flexural strength of type II composites increase by 25% and 27%, respectively at 2 wt% addition of clay. An oxy-acetylene torch test with a constant heat flux of 125 w/cm2 was used to investigate mass ablation rate of type II composites. The ablation rate has increased as the weight percentage of clay has increased. This is contradicting to type I composites with up to 6 wt% clay and type II composites with up to 4 wt% clay, which have improved thermal stability. The microstructure of the ablated composites was examined using scanning electron microscopy. Increased ablation rates are due to the reaction of charred matrix with nanoclay, which exposes bare fibers to the ablation front, resulting in higher mechanical erosion losses

A rare association of Kimura’s disease with chronic pulmonary aspergillosis

Kimura’s disease is a rare chronic benign inflammatory condition characterised by nodules of skin and soft tissue and lymphnodes. Eosinophilic infiltration is a prominent finding. It has been reported in association with various conditions like nephrotic syndrome, bronchial asthma, ulcerative colitis and aortitis syndrome. Hereby we present a case in medical literature to the best of our knowledge in Kimura’s disease in association with chronic cavitary pulmonary aspergillosis, which has never been reported. He was treated with antifungals, after which he responded clinically, eosinophilia has subsided and he is under regular follow up. Now This case report suggest possible role of chronic aspergillosis as a cause for Kimura’s disease

Prevalence of vitamin D deficiency in chronic obstructive pulmonary disease and it’s correlation with forced expiratory volume in one second: a tertiary care centre study

Background: Vitamin D deficiency is common all over the Indian subcontinent, with a prevalence of 70-100% in the general population. Vitamin D deficiency has a role in several diseases of the respiratory system including chronic obstructive pulmonary disease (COPD). Studies have shown that vitamin D deficient COPD patients have lower lung function measured by FEV1. We conducted a study to see prevalence of Vitamin D deficiency in COPD patients and it’s correlation with Forced Expiratory Volume in 1 second.Methods: A cross sectional observational study was performed in a tertiary care hospital in Hyderabad, Telangana during the period of one and half year. This included 104 COPD cases attending outpatient department of pulmonary medicine. Serum vitamin D levels were measured, and spirometry was done in all patients and data was analyzed accordingly.Results: Among 104 patients, 87 were males and 17 were females. Most of the study population (44.2%) was aged between 60-70 years. Mean BMI was 26.40 (±5.77) kg/m2. Majority of study populations (66.34%) were in GOLD stage 1 and 2. The mean Vitamin D value of the study population was 20.77±11.74ng/ml. Majority of the COPD patients were vitamin D deficient (69.2%). 25.0 % was severely deficient of vitamin D. The mean FEV1 volume (%) was 83.15±11.53, 60.97±17.47, 30.71±7.96 in sufficient, deficient and severe deficient patients.Conclusions: Vitamin D deficiency is common in COPD patients. Serum vitamin D deficiency increases with increased severity of COPD. There is positive correlation between serum vitamin D levels and post bronchodilator FEV1 (%).

DNA Binding and Photocleavage Studies of Cobalt(III) Ethylenediamine Pyridine Complexes: [Co(en)2(py)2]3+ and [Co(en)2(mepy)2]3+

Two novel cobalt(III) pyridine complexes (1) [Co(en)2(py)2]3+ and (2) [Co(en)2(mepy)2]3+ (en=ethylenediamine, py=pyridine, and mepy=methylpyridine) have been synthesized and characterized. The interaction of these complexes with calf thymus DNA was investigated by absorption, emission spectroscopy, viscosity measurements, DNA melting, and DNA photocleavage. Results suggest that the two complexes bind to DNA via groove mode and complex 2 binds more strongly to CT DNA than complex 1. Moreover, these Co(III) complexes have been found to promote the photocleavage of plasmid DNA pBR322 under irradiation at 365 nm, cytotoxicity results of complexes are also showing anticancer activity

Complexes of Ti(III), oxovanadium(IV), Fe(II), Co(II), Ni(II), Cu(II), Zn(II) and Hg(II) with gallacetophenone phenylhydrazone

916-918The complexes of Ti(III) oxovanadium(IV), Fe(II), Co(II), Ni(II), Cu(II), Zn(II), and Hg(II) with gallacetophenone phenylhydrazone (GAPPH) have been synthesized and characterized by analytical, conductivity, thermal, magnetic, infrared, electronic and ESR data. All the complexes have 1:2 (metal:ligand) stoichiometry. All the complexes are non-electrolytes in dimethylformamide, except Ti(III) complex which is 1:1 electrolyte. The infrared spectral data of the metal complexes indicate that GAPPH acts as a mononegative bidentate ligand coordinating through oxygen of o-hydroxy group and nitrogen of azomethine group. The electronic spectral data suggest that Ti(III) and Fe(II) complexes are octahedral. oxovanadium(IV) complex is tetragonal and Ni(II) and Cu(II) complexes are square-planar. The Co(II), Zn(II) and Hg(II

Synthesis, Structural Characterization, and Biological Activity Studies of Ni(II) and Zn(II) Complexes

Ni(II) and Zn(II) complexes were synthesized from tridentate 3-formyl chromone Schiff bases such as 3-((2-hydroxyphenylimino)methyl)-4H-chromen-4-one (HL 1 ), 2-((4-oxo-4H-chromen-3-yl)methylneamino)benzoic acid (HL 2 ), 3-((3-hydroxypyridin-2-ylimino)methyl)-4H-chromen-4-one (HL 3 ), and 3-((2-mercaptophenylimino)methyl)-4H-chromen-4-one (HL 4 ). All the complexes were characterized in the light of elemental analysis, molar conductance, FTIR, UV-VIS, magnetic, thermal, powder XRD, and SEM studies. The conductance and spectroscopic data suggested that, the ligands act as neutral and monobasic tridentate ligands and form octahedral complexes with general formula [M(L 1−4 )2]⋅nH 2 O (M = Ni(II) and Zn(II)). Metal complexes exhibited pronounced activity against tested bacteria and fungi strains compared to the ligands. In addition metal complexes displayed good antioxidant and moderate nematicidal activities. The cytotoxicity of ligands and their metal complexes have been evaluated by MTT assay. The DNA cleavage activity of the metal complexes was performed using agarose gel electrophoresis in the presence and absence of oxidant H 2 O 2 . All metal complexes showed significant nuclease activity in the presence of H 2 O 2

Synthesis and spectral studies of iron(III) and iron(II) complexes with 2,3-disubstituted quinazolin -4(3 H)-ones

1202-1206A number of Fe(III) and Fe(II) complexes of some O-N-O donors and bidentate O-O, and O-N donors in the form of 2,3-disubstituted quinazolin-4(3H)-ones have been synthesized and characterized based on analytical, conductivity, thermal, magnetic and infrared, electronic and Mossbauer spectral data. The analytical data of Fe(III) complexes with all the ligands with the exception of 2-methyl-3-carboxymethyl quinazolin-4(3H)- one (MCMQ) and 2-phenyl-3-carboxymethyl quinazolin-4(3H)- one (PCMQ), and all the complexes of Fe(II) show 1:2 (metal:ligand) stoichiometry. However, Fe(III) complexes of MCMQ and PCMQ are in 1:3 stoichiometry. The IR spectral data of complexes indicate that the ligands MHBQ and PHBQ act as uninegative tridentate and MCMQ and PCMQ act as uninegative bidentate ligands. The ligands viz 2-methyl-3-amine quinazolin-4(3H)-one (MAQ), 2-phenyl-3-amine quinazolin-4(3H)-one (PAQ), 2- methyl-3-uramino quinazolin-4(3H)- one (MUQ), 2-phenyl-3-uramino quinazolin-4(3H)- one (PUQ), 2-methyl-3-thiouramino quinazolin-4(3H)- one (MTUQ) and 2-phenyl-3-thiouramino quinazolin-4(3H)- one (PTUQ) act as neutral bidentate ligands. Octahedral geometry has been proposed for all the complexes based on electronic and Mossbauer spectral data

Synthesis, spectral characterisation, morphology, biological activity and DNA cleavage studies of metal complexes with chromone Schiff base

Cu(II), Co(II), Ni(II) and Zn(II) complexes have been synthesized using 3-((pyridine-2-ylimino)methyl)-4H-chromen-4-one as a ligand derived from 3-formyl chromone and 2-amino pyridine. All the complexes were characterised by analytical, conductivity, IR, electronic, magnetic, ESR, thermal, powder XRD and SEM studies. The analytical data revealed that the metal to ligand molar ratio is 1:2 in all the complexes. Molar conductivity data indicates that all the complexes are neutral in nature. On the basis of magnetic and electronic spectral data, octahedral geometry is proposed for all the complexes. Thermal behaviour of the synthesized complexes indicates the coordinated and lattice water molecules are present in the complexes. The X-ray diffraction data suggest a triclinic system for all compounds. Different surface morphologies were identified from SEM micrographs. All metal complexes exhibit fluorescence. The antimicrobial and nematicidal activity data show that metal complexes are more potent than the parent ligand. The DNA cleavage activity of the ligand and its metal complexes were observed in the presence of H2O2

Student Monitering using An Embedded Real Time Finger-Vein Recognition System

Abstract: In the academic institutions especially in professional institutions, attendance is a very important criterion which is used for various purposes. But, at the same time attendance status of the students should also be important to their Parent/Guardian, because of the mode of travel they use, which may be own/public vehicle and of course sometimes fraudulence by the words, becomes essential to track their ward. In the present traditional method, attendance involves the use of sheets of paper or books in taking student attendance, leads towards various challenges like time consuming, complexity of the calculations, occurrence of human errors, and could be stolen, damaged or lost. Thus, there is a need for a system that would eliminate all of these trouble spots. Our finger print recognition system would provide the needed solution. In this attendance management system Rather answering for attendance individual has to pass his/her thumb over the fingerprint scanner and the fingerprint is compared against a list of preregistered users, and once a match are made, the individual will be registered. As soon as the attendance of a student is registered, a message would be sent to his/her Parent/Guardian. at the moment itself about his presence in the class, which makes them the avoidance of tracking or worrying about their ward. And also we are adding time table alert system for department. Here we design an embedded system to store the time table of a class and send an alert message to the faculty just few minutes before the commencement of the class